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Real-Time Simulation and Visualization of Cancer Cells

My Role 

PhD Project

Status

On Going (2nd Year)

Previous Work

•Single Cell Visualization for propelling Drug discovery

 

•Interactions of multiple cells is missing.

 

• Accuracy of simulation and reproducing results is key.

SiViT (Goltsov et al., 2012)
Scaling single cell

Proposed Project

•Scaling up the pre-existing model to accommodate for interactions between 1M cells.

 

•Using Distributed computing methods to speed up the simulation.

 

• Maintain the accuracy of the simulation using efficient synchronization methods

Cell Models

There are 2 types of models that need to be coupled:

  • Cell Signalling (Protein interactions of cells)

  • Physical models (Forces between cells and their effects)

Scem: Forces
Network schematic. The model of the PI3K/PTEN/AKT and RAF/MEK/ERK signalling network. (Goltsov et al., 2012)

Method

Spatialos.png
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